Resources available on this page include application notes, posters and publications. Application notes are written by SKi and provide the experimental details for a specific type of experiment or theoretical concept. Posters were presented at various conferences. Publications include publications made by our customers in a peer reviewed context.

Application Notes

Nanopore Optical Interferometry
Proteins recruited from complex mixutres
SKi Sensors 4FB Biochips
Therapeutic Antibody Characterization
Benchmarking NPOI vs SPR
Antibody/Antigen Characterization
Surface Stabilization Following Indirect Capture
Characterizing Slow Off Rates
Characterization of Small Molecule to Protein Binding
Assay Designs for Immobilization of His-tagged Proteins
Affinity Capture-Mass Spectrometry


Antibody screening and Characterization by Nanopore Optical Interferoometry
Label-free detection of DNA-DNA, DNA-RNA and DNA-Protein Interactions in Real Time Using Nano-Porous Surface Combined With Light Interferometry
Nanopore Optical Interferometry (NPOI) Used To Characterize Antibody-Antigen Interactions
Label-free detection of biomolecular interactions in real time with a novel nano-porous silicon based biosensor platform
The Growth Inhibitor TOE1 Interacts with p53 and Modulates Its Transactivation

Peer-reviewed Publications

  1. Latterich, M. and Corbeil, J. (2008) "Label-free detection of biomolecular interactions in real time with a nano-porous silicon based detection method." Proteome Science, 6:31.
  2. Schasfoort, R., et al. (2008) SPR instrumentation (pp 93–116). RSC Publishing, Cambridge.
  3. Sperandio, S., et al. (2009) "TOE1 interacts with p53 to modulate its transactivtaion potential." FEBS Letters, 583:2165.
  4. Dubois, D.Y., et al. (2009) "A C-truncated glutamyl-tRNA synthetase specific for rRNA Glu is stimulated by its free complementary distal domain: mechanistic and evolutionary implications." Biochemistry, 48:6012.
  5. Halawain, D., et al. (2009) "Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation." Mol. Cell. Biol., 29:4484.
  6. Sanchez, A.B., et al. (2010) "A general process for the development of peptide-based immunoassays for monoclonal antibodies." Cancer Chemother. Pharmocol., 66:919.
  7. Singh, P., et al. (2010) "Application of porous silicon thin films in solar cells and biosensors." JOM, 62:15.
  8. De Vos, K. (2010) Label-free silicon photonics biosensor platform with microring resonators. Universiteit Gent, Gent.
  9. Sadan, A. and Sadana, N. (2011) Handbook of Biosensors and Biosensor Kinetics. Elsevier, Amsterdam.
  10. Huot, J.L., et al. (2011) "Gln-tRNAgln synthesis in a dynamic transamidosome from Helicobacter pylori, where GluRS2 hydrolyzes excess Glu-tRNAGln.." Nucleic acids research, 39:9306.
  11. Kussrow, A., et al. (2012) "Interferometric methods for label-free molecular interaction studies." Anal. Chem., 84:779.
  12. Kussrow, A., et al. (2014) "Epitope mapping of the 2009 pandemic and the A/Brisbane/59/2007 seasonal (H1N1) influenze virus haemagglutinins using mAbs and escape mutants." Anal. Chem., 95:2377.
  13. Muñoz, E. and Ricklin, D. (2014) Analysis of molecular interactions by surface plasmon resonance spectroscopy Structure elucidation in organic chemistry: The search for the right tools (pp 361–392). Wiley, Weinheim.
  14. Urmann, K., et al. (2015) Porous silicon biosensors employing emerging capture probes Electrocehcmially Engineered Nanoporous Materials (pp 93–116). Springer International Publishing, Cham.
  15. Nakayama, N., et al. (2016) "Developments of mass spectrometry-based technologies for effective drug development linked with clinial proteomics." Drug Met. Pharmacokin., 31:3.
  16. Kipps, T.J., et al. (2016) "Methods for detecting antibodies." U.S. Patent 9,250,233. Washington, DC US: U.S. Patent and Trademark Office.
  17. Kipps, T.J., et al. (2016) "Methods for detecting antibodies." U.S. Patent 20,160,146,829. Washington, DC US: U.S. Patent and Trademark Office.